Blood viscosity and you can blood pressure: part away from temperatures and you can hyperglycemia

Blood viscosity and you can blood pressure: part away from temperatures and you can hyperglycemia

Yildirim Cinar, An excellent. Mete Senyol, Kamber Duman, Blood best hookup sites for couples viscosity and blood pressure levels: part off temperatures and hyperglycemia, American Journal regarding Hypertension, Frequency step one4, Thing 5, , Profiles 433–438,


We planned a study to research the relations among blood pressure (BP), viscosity, and temperature in healthy subjects and among BP, viscosity, and glucose in diabetics. With simple random sampling method, 53 healthy and 29 diabetes mellitus (DM) type II subjects were selected. Parameters were determined with capillary viscometer and glucometer at 22°C, 36.5°C, and 39.5°C in healthy subjects, and at 22°C on diabetic patients during OGTT with 75 g of glucose. Statistical evaluations of the data were made with regression analysis, Student t test, Spearman’s correlation, and analysis of variance. When temperature decreased from 36.5°C to 22°C, blood viscosity increased %. This increase resulted in a % decrease in blood flow rate. According to the Hagen-Poiseuille equation, the required BP increase for compensation of the resulting tissue ischemia was %. Also, a % decrease in erythrocyte deformability and % increase in plasma viscosity were seen. When temperature increased from 36.5° to 39.5°C, blood viscosity decreased %. This caused % decrease in blood flow rate, and % decrease in BP, according to the equation. Erythrocyte deformability increase of 9.92% and plasma viscosity decrease of 4.99% arose from the temperature rise. There is a correlation between total data for temperatures and viscosities (r = ?0.84, P < .001). When the mean value of blood glucose increased from 100 to 400 mg/dL, viscosity increased 25% (r = 0.59, P = .002). In this state, blood flow rate decrease was 20% and BP increase for physiological compensation was 25%. Consequently, temperature, glucose and viscosity levels of blood are important factors for BP. Am J Hypertens 2001;–438 © 2001 American Journal of Hypertension, Ltd.

The purpose of our very own data will be to research the relationship certainly temperatures, glucose concentration, and you will viscosity from blood and you can plasma, also to determine its consequences into the hypertension (BP) centered on Hagen-Poiseuille’s hydrodynamics formula.

If the human circulatory system is considered as a closed system, hemodynamic equilibrium can be determined according to Poiseuille’s equation through the pressure, viscosity, flow rate, velocity of blood, and vessel diameter. Viscosity can be defined as the resistance of fluids against flow. The resistance for blood circulation includes friction between the blood elements and between the vessel lumen and blood. To make a fluid flow, the application of energy is required. Therefore, the energy of the circulatory system is spent in correlation with the viscosity level of blood. Energy forms of the circulatory system are BP and blood flow velocity. The velocity (v) and pressure of blood flow can be determined with Poiseuille’s equation as v = 1/4?L (F1 ? F2) (a 2 ? r 2 ), and also BP rate (Q) can be expressed from the above equation as Q = ?a 4 /8 ?L (F1 ? F2), where ? is the viscosity of the fluid, F1 and F2 are the initial and the final cross sectional pressures of blood, L is the length, a is the radius of vessel, and r is the distance from the center of the vessel for a flowing particle. 1, 2 Thus, to keep the equilibrium of the equation constant in the circulatory system, BP will increase when viscosity increases.

Blood viscosity and you will blood pressure levels: role off temperature and you can hyperglycemia

This has been found that anywhere between % and you may % philosophy off hematocrit, all of the 11% rise in hematocrit develops bloodstream viscosity from the 20%. Contained in this condition, considering Poiseuille’s formula, blood supply price decrease by %, that could result in structure ischemia. To save the fresh new circulatory system for the equilibrium (that’s, remaining the disperse rate enough and you can preventing tissue ischemia), good 20% escalation in BP otherwise cuatro.66% vasodilation required. 3 not, the human being circulatory system is perhaps not an accurate finalized system, since the blood viscosity will likely be changed on the consumption out-of dinner or drugs. 4–8 Simultaneously, the consequences away from fat molecules as well as some medications on blood viscosity and hemodynamics including BP were reported. While the atherosclerotic boats try not to dilate well enough once the a reaction to vasodilator medications, it’s been advised one to improved blood viscosity can just only getting settled having an excellent BP escalation in like products. 9–twelve Plus, the latest dating one of BP, nightmare, coagulation, blood supply velocity, and you may blood viscosity had been demonstrated via the values out-of hemodynamics. thirteen, 14

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